Analytical Validation and Biological Evaluation of a High–Molecular-Weight Adiponectin ELISA | Zendy

Madhur K. Sinha | Zendy; Traci Songer | Zendy; Qiang Xiao | Zendy; John H. Sloan | Zendy; Jin Wang | Zendy; Shaoquen Ji | Zendy; William E. Alborn | Zendy; Randy A Davis | Zendy; Michael M. Swarbrick | Zendy; Kimber L. Stanhope | Zendy; Bruce M. Wolfe | Zendy; Peter J. Havel | Zendy; Todd Schraw | Zendy; Robert J. Konrad | Zendy; Philipp E. Scherer | Zendy; Jehangir Mistry | Zendy

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Analytical Validation and Biological Evaluation of a High–Molecular-Weight Adiponectin ELISA

Author(s) -

Madhur K. Sinha,

Traci Songer,

Qiang Xiao,

John H. Sloan,

Jin Wang,

Shaoquen Ji,

William E. Alborn,

Randy A Davis,

Michael M. Swarbrick,

Kimber L. Stanhope,

Bruce M. Wolfe,

Peter J. Havel,

Todd Schraw,

Robert J. Konrad,

Philipp E. Scherer,

Jehangir Mistry

Publication year - 2007

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2007.090670

Subject(s) - adiponectin , chemistry , chromatography , detection limit , medicine , endocrinology , insulin , insulin resistance , biology

Of the 3 circulating multimeric forms of adiponectin, the high-molecular-weight (HMW) form, as measured by size-exclusion and/or immunoblotting techniques, is a better index of insulin sensitivity for monitoring health and disease than is total adiponectin. We aimed to develop a simple ELISA to measure HMW adiponectin.

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