Risk Stratification for Heart Failure and Death in an Acute Coronary Syndrome Population Using Inflammatory Cytokines and N-Terminal Pro-Brain Natriuretic Peptide
Author(s) -
Peter A. Kavsak,
Dennis T. Ko,
Alice Newman,
Glenn E. Palomaki,
Viliam Lustig,
Andrew R. MacRae,
Allan S. Jaffe
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.090613
Subject(s) - n terminal pro brain natriuretic peptide , medicine , risk stratification , brain natriuretic peptide , natriuretic peptide , heart failure , acute coronary syndrome , cardiology , population , inflammation , proinflammatory cytokine , myocardial infarction , environmental health
Inflammation in acute coronary syndrome (ACS) can identify those at greater long-term risks for heart failure (HF) and death. The present study assessed the performance of interleukin (IL)-6, IL-8, and monocyte chemoattractant protein-1 (MCP-1) (cytokines involved in the activation and recruitment of leukocytes) in addition to known biomarkers [e.g., N-terminal pro-brain natriuretic peptide (NT-proBNP)] for predicting HF and death in an ACS population.
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