Open AccessExpanded Instrument Comparison of Amplicon DNA Melting Analysis for Mutation Scanning and Genotyping
Author(s) -
Mark G. Herrmann,
Jacob Durtschi,
Carl T. Wittwer,
Karl V. Voelkerding
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.088120
Subject(s) - amplicon , genotyping , genotype , heterozygote advantage , high resolution melt , locus (genetics) , compound heterozygosity , microbiology and biotechnology , biology , melting curve analysis , genetics , melting temperature , polymerase chain reaction , gene , mutation , materials science , composite material
Additional instruments have become available since instruments for DNA melting analysis of PCR products for genotyping and mutation scanning were compared. We assessed the performance of these new instruments for genotyping and scanning for mutations.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom