Assessing Quality and Functionality of DNA from Fresh and Archival Dried Blood Spots and Recommendations for Quality Control Guidelines
Author(s) -
Malin Sjöholm,
Joakim Dillner,
Joyce Carlson
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.087510
Subject(s) - dna extraction , dna , snp , population , biology , lysis , polymerase chain reaction , single nucleotide polymorphism , microbiology and biotechnology , medicine , genetics , genotype , gene , environmental health
Dried blood spots (DBS) are a convenient and inexpensive method for biobanking. Although many countries have established population-based DBS biobanks from neonatal screening programs, the quality and usefulness of DNA from DBS have not been extensively assessed.
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