Breast Cancer Diagnosis and Prognosis through Quantitative Measurements of Serum Glycan Profiles
Author(s) -
Zuzana Kyseľová,
Yehia Mechref,
Pilsoo Kang,
John A. Goetz,
Lacey E. Dobrolecki,
George W. Sledge,
Lauren A. Schnaper,
Robert J. Hickey,
Linda H. Malkas,
Miloš V. Novotný
Publication year - 2008
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.087148
Subject(s) - glycan , fucosylation , glycosylation , glycomics , breast cancer , glycoprotein , cancer , chemistry , glycome , computational biology , biochemistry , biology , genetics
Glycosylated proteins play important roles in cell-to-cell interactions, immunosurveillance, and a variety of receptor-mediated and specific protein functions through a highly complex repertoire of glycan structures. Aberrant glycosylation has been implicated in cancer for many years.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom