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Intraindividual Stability of Human Erythrocyte Cholinesterase Activity
Author(s) -
Lee J. Lefkowitz,
Joseph M Kupina,
Nigel L Hirth,
Rachel M. Henry,
Georgia Y Noland,
J Barbee,
Joey Y. Zhou,
Coleen Weese
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.085258
Subject(s) - cholinesterase , medicine , technician , physiology , toxicology , biology , electrical engineering , engineering
Erythrocyte cholinesterase (RBC-ChE) activities serve as useful and sensitive biomarkers to monitor exposure to cholinesterase-inhibiting substances, such as chemical warfare nerve agents and pesticides. Although the interindividual variation of RBC-ChE is well characterized, the magnitude of intraindividual variation for RBC-ChE remains controversial. An accurate measure of intraindividual variation is critical for establishing the appropriate frequency of RBC-ChE testing.

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