Increased Concentrations of Antibody-Bound Circulatory Cell-Free DNA in Rheumatoid Arthritis | Zendy

Xiaoyan Zhong | Zendy; Ines von Mühlenen | Zendy; Ying Li | Zendy; Anjeung Kang | Zendy; Anurag Gupta | Zendy; Alan Tyndall | Zendy; Wolfgang Holzgreve | Zendy; Sinuhe Hahn | Zendy; Paul Hasler | Zendy

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Increased Concentrations of Antibody-Bound Circulatory Cell-Free DNA in Rheumatoid Arthritis

Author(s) -

Xiaoyan Zhong,

Ines von Mühlenen,

Ying Li,

Anjeung Kang,

Anurag Gupta,

Alan Tyndall,

Wolfgang Holzgreve,

Sinuhe Hahn,

Paul Hasler

Publication year - 2007

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.084509

Subject(s) - rheumatoid arthritis , antibody , cell free fetal dna , dna , plasma cell , immunology , pathogenesis , medicine , microbiology and biotechnology , glyceraldehyde 3 phosphate dehydrogenase , cell , endocrinology , chemistry , biology , enzyme , dehydrogenase , biochemistry , genetics , prenatal diagnosis , pregnancy , fetus

Increased concentrations of cell-free DNA have been found in several disorders and have been interpreted as evidence of increased rates of cell death or turnover. Evidence from in vitro and animal experiments suggests that DNA may play a role in the pathogenesis of rheumatoid arthritis (RA).

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