Reliable Screening for a Pain-Protective Haplotype in the GTP Cyclohydrolase 1 Gene (GCH1) Through the Use of 3 or Fewer Single Nucleotide Polymorphisms | Zendy

Jörn Lötsch | Zendy; Inna Belfer | Zendy; Anja Kirchhof | Zendy; Bikash Kumar Mishra | Zendy; Mitchell B. Max | Zendy; Alexandra Doehring | Zendy; Michael Costigan | Zendy; Clifford J. Woolf | Zendy; Gerd Geißlinger | Zendy; Irmgard Tegeder | Zendy

Open Access

Reliable Screening for a Pain-Protective Haplotype in the GTP Cyclohydrolase 1 Gene (GCH1) Through the Use of 3 or Fewer Single Nucleotide Polymorphisms

Author(s) -

Jörn Lötsch,

Inna Belfer,

Anja Kirchhof,

Bikash Kumar Mishra,

Mitchell B. Max,

Alexandra Doehring,

Michael Costigan,

Clifford J. Woolf,

Gerd Geißlinger,

Irmgard Tegeder

Publication year - 2007

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.082883

Subject(s) - haplotype , dbsnp , genetics , in silico , biology , single nucleotide polymorphism , pyrosequencing , gene , genotype

A haplotype in the GTP cyclohydrolase 1 (dopa-responsive dystonia) gene (GCH1) is associated with decreased persistent pain. The aim of the present study was to develop a screening method for the pain-protective haplotype.

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