International Comparison of C-Peptide Measurements
Author(s) -
Hsiao-Mei Wiedmeyer,
Kenneth S. Polonsky,
Gary L. Myers,
Randie R. Little,
Carla J. Greenbaum,
David E. Goldstein,
Jerry P. Palmer
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.081570
Subject(s) - comparability , peptide , normalization (sociology) , chromatography , c peptide , confidence interval , medicine , chemistry , statistics , mathematics , insulin , biochemistry , combinatorics , sociology , anthropology
C-peptide measurement has been widely used as a marker of insulin secretion in patients with diabetes. We assessed the comparability of C-peptide results obtained with different methods and by different laboratories and determined whether C-peptide results could be harmonized by normalization with a WHO reference reagent or with plasma.
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