Open AccessValidation of a CYP2D6 Genotyping Panel on the NanoChip Molecular Biology Workstation
Author(s) -
Hong-Kee Lee,
Lionel D. Lewis,
Gregory J. Tsongalis,
Bernard C Schur,
Paul J. Jannetto,
Steven Wong,
Kiang-Teck J. Yeo
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.081539
Subject(s) - genotyping , biology , computational biology , genetics , workstation , genotype , computer science , gene , operating system
CYP2D6 is a highly polymorphic phase I enzyme that metabolizes 20%-25% of clinically used drugs. The objective of this study was to validate a CYP2D6 genotyping assay with the NanoChip Molecular Biology Workstation.
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