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Cell-Free mRNA Concentrations of Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator Are Increased in the Plasma of Pregnant Women with Preeclampsia
Author(s) -
Yuditiya Purwosunu,
Akihiko Sekizawa,
Keiko Koide,
Antonio Farina,
Noroyono Wibowo,
Gulardi Hanifa Wiknjosastro,
Shiho Okazaki,
Hiroshi Chiba,
Takashi Okai
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.081372
Subject(s) - preeclampsia , endocrinology , plasminogen activator , medicine , plasminogen activator inhibitor 1 , tissue plasminogen activator , messenger rna , andrology , chemistry , biology , pregnancy , gene , biochemistry , genetics
Detection of placental mRNA in maternal plasma has been reported in high-risk pregnancies. We attempted to investigate the concentrations of plasminogen activator inhibitor-1 (PAI-1) and tissue-type plasminogen activator (tPA) mRNA in maternal plasma in preeclampsia.

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