Natural Calcium Isotopic Composition of Urine as a Marker of Bone Mineral Balance | Zendy

Joseph L. Skulan | Zendy; Thomas D. Bullen | Zendy; Ariel D. Anbar | Zendy; J. Edward Puzas | Zendy; Linda Shackelford | Zendy; Adrian LeBlanc | Zendy; Scott M. Smith | Zendy

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Natural Calcium Isotopic Composition of Urine as a Marker of Bone Mineral Balance

Author(s) -

Joseph L. Skulan,

Thomas D. Bullen,

Ariel D. Anbar,

J. Edward Puzas,

Linda Shackelford,

Adrian LeBlanc,

Scott M. Smith

Publication year - 2007

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.080143

Subject(s) - urine , calcium , bone mineral , chemistry , isotopes of calcium , medicine , osteoporosis , biochemistry , organic chemistry

We investigated whether changes in the natural isotopic composition of calcium in human urine track changes in net bone mineral balance, as predicted by a model of calcium isotopic behavior in vertebrates. If so, isotopic analysis of natural urine or blood calcium could be used to monitor short-term changes in bone mineral balance that cannot be detected with other techniques.

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