Hyperhomocysteinemia and Myocardial Expression of Brain Natriuretic Peptide in Rats
Author(s) -
Markus Herrmann,
Omid Taban-Shoma,
Ulrich Hübner,
Anette Pexa,
Heiko Kilter,
Natalia Umanskaya,
Rainer H. Straub,
Michael Böhm,
Wolfgang Herrmann
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.077859
Subject(s) - hyperhomocysteinemia , brain natriuretic peptide , medicine , endocrinology , natriuretic peptide , methionine , homocysteine , heart failure , chemistry , biochemistry , amino acid
Hyperhomocysteinemia (HHcy) has been linked to impaired left ventricular function and clinical class in patients with chronic heart failure. We hypothesized that HHcy stimulates myocardial brain natriuretic peptide (BNP) expression and induces adverse left ventricular remodeling.
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