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Circulating Concentrations of Growth-Differentiation Factor 15 in Apparently Healthy Elderly Individuals and Patients with Chronic Heart Failure as Assessed by a New Immunoradiometric Sandwich Assay
Author(s) -
Tibor Kempf,
Rüdiger Horn-Wichmann,
Georg Brabant,
Timo Peter,
Tim Allhoff,
Gunnar Klein,
Helmut Drexler,
Nina Johnston,
Lars Wallentin,
Kai C. Wollert
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.076828
Subject(s) - gdf15 , immunoradiometric assay , biomarker , medicine , confounding , nephelometry , polyclonal antibodies , monoclonal , endocrinology , antibody , immunology , monoclonal antibody , radioimmunoassay , biology , biochemistry
Growth-differentiation factor 15 (GDF15) is a member of the transforming growth factor beta (TGF-beta) cytokine superfamily. There has been increasing interest in using circulating GDF15 as a biomarker in patients, for example those with cardiovascular disease.

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