Platelet Resistance to the Antiaggregatory Cyclic Nucleotides in Central Obesity Involves Reduced Phosphorylation of Vasodilator-Stimulated Phosphoprotein | Zendy

Isabella Russo | Zendy; Paola Del Mese | Zendy; Gabriella Doronzo | Zendy; Alessandro De Salve | Zendy; M Secchi | Zendy; Mariella Trovati | Zendy; Giovanni Anfossi | Zendy

Open Access

Platelet Resistance to the Antiaggregatory Cyclic Nucleotides in Central Obesity Involves Reduced Phosphorylation of Vasodilator-Stimulated Phosphoprotein

Author(s) -

Isabella Russo,

Paola Del Mese,

Gabriella Doronzo,

Alessandro De Salve,

M Secchi,

Mariella Trovati,

Giovanni Anfossi

Publication year - 2007

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.076208

Subject(s) - medicine , endocrinology , phosphorylation , phosphoprotein , cyclic nucleotide , nucleotide , platelet , kinase , platelet activation , protein kinase a , chemistry , vasodilation , biochemistry , gene

Impairment of platelet response to antiaggregatory agents is seen in individuals with central obesity and may play a role in the increased cardiovascular risk associated with obesity. In this study we evaluated whether this impairment involves the antiaggregatory pathways regulated by cAMP and cGMP.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research