Open AccessAccuracy and Biological Variation of Human Serum Paraoxonase 1 Activity and Polymorphism (Q192R) by Kinetic Enzyme Assay
Author(s) -
Richard W. Browne,
Stephen T. Koury,
Susan Marion,
Gregory E. Wilding,
Paola Muti,
Maurizio Trevisan
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.074559
Subject(s) - pon1 , paraoxonase , genotype , aryldialkylphosphatase , arylesterase , biology , microbiology and biotechnology , enzyme , genetics , biochemistry , gene
Paraoxonase 1 (PON1) phenotype is a better predictor of atherosclerosis risk than are PON1 genetic polymorphisms alone. Larger studies are required to determine the role of PON1 and there is a need for standardized PON1 assays between laboratories.
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