Open AccessTransferrin and Apolipoprotein C-III Isofocusing Are Complementary in the Diagnosis of N- and O-Glycan Biosynthesis Defects
Author(s) -
Suzan Wopereis,
Stephanie Grünewald,
Karin Huijben,
Éva Morava,
Rosella Mollicone,
Baziel G.M. van Engelen,
Dirk J. Lefeber,
Ron A. Wevers
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.073940
Subject(s) - glycan , transferrin , glycosylation , biosynthesis , biochemistry , mucin , apolipoprotein b , isoelectric focusing , glycoprotein , chemistry , biology , microbiology and biotechnology , gene , cholesterol , enzyme
Apolipoprotein C-III (apoC-III) isoelectric focusing (IEF) can be used to detect abnormalities in the biosynthesis of core 1 mucin-type O-glycans.
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