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Increased Plasma Concentrations of Antiprothrombin Antibodies in Women with Recurrent Spontaneous Abortions
Author(s) -
Laura Sabatini,
Michela Torricelli,
Valentina Scaccia,
Daniela Fineschi,
Monica Pescaglini,
Laura Gasparri,
Pasquale Florio,
Felice Petraglia
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.073098
Subject(s) - medicine , antibody , gestation , abortion , pregnancy , pathogenesis , antiphospholipid syndrome , clinical significance , immunopathology , live birth , immunology , etiology , biology , genetics
Antiphospholipid antibodies are associated with recurrent fetal loss, but the clinical relevance of antiprothrombin (aPT) antibodies remains controversial. This study was designed to evaluate the relationship of plasma concentrations of aPT antibodies (IgG, IgM, and IgA isotypes) and recurrent spontaneous abortion (RSA) not associated with antiphospholipid-antibody syndrome.

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