A Gray Zone Assigned to Inconclusive Results of Quantitative Diagnostic Tests: Application to the Use of Brain Natriuretic Peptide for Diagnosis of Heart Failure in Acute Dyspneic Patients | Zendy

Joël Coste | Zendy; Patrick Jourdain | Zendy; J. Pouchot | Zendy

Open Access

A Gray Zone Assigned to Inconclusive Results of Quantitative Diagnostic Tests: Application to the Use of Brain Natriuretic Peptide for Diagnosis of Heart Failure in Acute Dyspneic Patients

Author(s) -

Joël Coste,

Patrick Jourdain,

J. Pouchot

Publication year - 2006

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.072280

Subject(s) - medicine , heart failure , brain natriuretic peptide , emergency department , cardiology , natriuretic peptide , cutoff , clinical practice , acute decompensated heart failure , heart disease , physical therapy , physics , quantum mechanics , psychiatry

Most quantitative diagnostic tests do not perfectly differentiate between persons with and without a given disease. We present a simple method to construct a 3-zone partition for quantitative tests results, including positive and negative zones and a gray zone between, and we describe its use in the diagnosis of heart failure by brain natriuretic peptide (BNP) measurement in acute dyspneic patients.

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