In Situ Amplified Chemiluminescent Detection of DNA and Immunoassay of IgG Using Special-Shaped Gold Nanoparticles as Label | Zendy

Zhouping Wang | Zendy; Jianqiang Hu | Zendy; Yan Jin | Zendy; Xin Yao | Zendy; Jinghong Li | Zendy

Open Access

In Situ Amplified Chemiluminescent Detection of DNA and Immunoassay of IgG Using Special-Shaped Gold Nanoparticles as Label

Author(s) -

Zhouping Wang,

Jianqiang Hu,

Yan Jin,

Xin Yao,

Jinghong Li

Publication year - 2006

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.071399

Subject(s) - luminol , chemiluminescence , detection limit , chemistry , immunoassay , oligonucleotide , colloidal gold , dna , chromatography , microbiology and biotechnology , nanoparticle , biochemistry , antibody , nanotechnology , materials science , biology , immunology

Au(III) catalyzed luminol chemiluminescence (CL) is classic in luminescence analysis. Recently, spherical gold nanoparticles (Au-NPs) were found displaying far stronger catalytic activity on luminol CL than that of Au(III). Some methods based on Au-NPs probes have been developed for DNA detection or immunoassay. However, more complicated labeling or stripping procedures are often inescapable in these protocols.

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