Measurement of Urinary Metanephrines to Screen for Pheochromocytoma in an Unselected Hospital Referral Population | Zendy

Keith L. Brain | Zendy; Jonathan Kay | Zendy; Brian Shine | Zendy

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Measurement of Urinary Metanephrines to Screen for Pheochromocytoma in an Unselected Hospital Referral Population

Author(s) -

Keith L. Brain,

Jonathan Kay,

Brian Shine

Publication year - 2006

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.070805

Subject(s) - metanephrine , normetanephrine , metanephrines , pheochromocytoma , medicine , urinary system , population , urology , gold standard (test) , environmental health

Despite the rarity of pheochromocytoma, diagnosis is important because of the dangers of uncontrolled severe hypertension and the availability of very effective surgical treatment. Urinary or plasma catecholamines or catecholamine derivatives are commonly used to screen for pheochromocytomas before imaging, but data from 24-h urinary metanephrine results, patient age, and sex may better predict tumors in populations with a low pretest probability.

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