Real-Time PCR to Identify Variola Virus or Other Human Pathogenic Orthopox Viruses
Author(s) -
Natale Scaramozzino,
Audrey Ferrier-Rembert,
AnneLaure Favier,
Corinne Rothlisberger,
Stéphane Richard,
JeanMarc Crance,
Helmut E. Meyer,
Daniel Garín
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.068635
Subject(s) - orthopoxvirus , monkeypox , cowpox , variola virus , virology , poxviridae , vaccinia , smallpox , cowpox virus , biology , smallpox virus , gene , vaccination , genetics , recombinant dna
Variola virus (family Poxviridae, genus Orthopoxvirus) and the closely related cowpox, vaccinia, and monkeypox viruses can infect humans. Efforts are mounting to replenish the smallpox vaccine stocks, optimize diagnostic methods for poxviruses, and develop new antivirals against smallpox, because it is feared that variola virus might be used as a weapon of bioterrorism.
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