Repair of Infarcted Myocardium by an Extract of Geum japonicum with Dual Effects on Angiogenesis and Myogenesis | Zendy

Ming Li | Zendy; CheukMan Yu | Zendy; Lei Cheng | Zendy; Mei Wang | Zendy; Xuemei Gu | Zendy; KK Lee | Zendy; Tian Wang | Zendy; Yn Tz Sung | Zendy; John E. Sanderson | Zendy

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Repair of Infarcted Myocardium by an Extract of Geum japonicum with Dual Effects on Angiogenesis and Myogenesis

Author(s) -

Ming Li,

CheukMan Yu,

Lei Cheng,

Mei Wang,

Xuemei Gu,

KK Lee,

Tian Wang,

Yn Tz Sung,

John E. Sanderson

Publication year - 2006

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.068247

Subject(s) - angiogenesis , myocardial infarction , in vivo , myocyte , cardiology , infarction , medicine , ejection fraction , myogenesis , pharmacology , biology , heart failure , microbiology and biotechnology

It has become apparent recently that cardiac myocytes can divide after myocardial infarction, a circumstance that challenges the orthodox view that myocytes may be terminally differentiated. Replacement of the necrosed heart tissue by newly regenerated functional myocardium is a therapeutic ideal, but attempts to reconstitute functional myocardia and coronary vessels have been less successful.

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