Oxidized Forms of Glutathione in Peripheral Blood as Biomarkers of Oxidative Stress
Author(s) -
Ranieri Rossi,
Isabella DalleDonne,
Aldo Milzani,
Daniela Giustarini
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2006.067793
Subject(s) - glutathione , oxidative stress , menadione , glutathione disulfide , chemistry , malondialdehyde , in vivo , oxidative phosphorylation , biochemistry , chromatography , enzyme , biology , microbiology and biotechnology
Reduced glutathione (GSH) and its redox forms, glutathione disulfide (GSSG) and glutathionylated proteins (PSSG), are biomarkers of oxidative stress, but methodologic artifacts can interfere with their measurement. We evaluated the importance of correct sample handling during the preanalytical phase for GSH, GSSG, and PSSG measurement.
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