Increased Plasma Concentration of Matrix Metalloproteinase-7 in Patients with Coronary Artery Disease | Zendy

Lennart Nilsson | Zendy; Lena Jonasson | Zendy; Johnny Nijm | Zendy; Anders Hamsten | Zendy; Per Eriksson | Zendy

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Increased Plasma Concentration of Matrix Metalloproteinase-7 in Patients with Coronary Artery Disease

Author(s) -

Lennart Nilsson,

Lena Jonasson,

Johnny Nijm,

Anders Hamsten,

Per Eriksson

Publication year - 2006

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2006.067439

Subject(s) - coronary artery disease , matrix metalloproteinase , inflammation , medicine , tissue inhibitor of metalloproteinase , metalloproteinase , immunology , pathology , chemistry , endocrinology

Plaque rupture is often associated with breakdown of the extracellular matrix in the shoulder region of a plaque. We tested whether plasma concentrations of various matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase-1 (TIMP-1) could serve as markers for plaque instability as well as relationships between plasma MMPs and inflammatory markers.

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