Open AccessPerformance of a New-Generation Chemiluminescent Assay for Hepatitis B Surface Antigen
Author(s) -
Dan Chen,
Lawrence A. Kaplan
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.064063
Subject(s) - hbsag , medicine , serology , neutralization , virology , antigen , antibody , hepatitis b , hepatitis b virus , immunology , microbiology and biotechnology , virus , biology
The usual criteria for analysis of hepatitis B surface antigen (HBsAg) are detection of HBsAg and result confirmation by antibody neutralization. We observed that with the Immulite 2000 HBsAg assay [Diagnostics Product Corporation (DPC)] a relatively high percentage of weakly reactive (WR) samples did not pass the neutralization step.
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