Open AccessUtility of N-Terminal Pro-B-Type Natriuretic Peptide to Differentiate Cardiac Diseases from Noncardiac Diseases in Young Pediatric Patients
Author(s) -
Angelika HammererLercher,
Ralf Geiger,
Johannes Mair,
Christoph Url,
Gerald Tulzer,
Evelyn Lechner,
Bernd Puschendorf,
Rudolf Sommer
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.060608
Subject(s) - medicine , natriuretic peptide , confidence interval , percentile , population , area under the curve , pediatrics , receiver operating characteristic , mann–whitney u test , cardiology , heart failure , environmental health , mathematics , statistics
Previous studies comparing children with cardiac disease with children with lung disease or healthy children indicated that natriuretic peptides are promising markers in pediatric patients. The aim of this study was to further clarify the diagnostic usefulness of N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements in a less preselected population of children younger than 3 years, a population in which clinical symptoms are frequently unspecific.
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