Open AccessAssay for the Measurement of Copeptin, a Stable Peptide Derived from the Precursor of Vasopressin
Author(s) -
Nils G. Morgenthaler,
Joachim Struck,
Christine Alonso,
Andreas Bergmann
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.060038
Subject(s) - copeptin , vasopressin , medicine , endocrinology , sepsis , prohormone , chemistry , arginine , analyte , chromatography , amino acid , biochemistry , hormone
Arginine vasopressin (AVP) is a key regulator of water balance, but its instability makes reliable measurement difficult and precludes routine use. We present a method for quantifying AVP release by use of copeptin, a glycopeptide comprising the C-terminal part of the AVP prohormone.
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