Disparate LDL Phenotypic Classification among 4 Different Methods Assessing LDL Particle Characteristics
Author(s) -
Wayne Ensign,
Nicole Hill,
Christopher B. Heward
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.059949
Subject(s) - ldl cholesterol , subclass , phenotype , chemistry , chromatography , medicine , computational biology , cholesterol , biology , biochemistry , immunology , antibody , gene
Our study seeks to clarify the extent of differences in analytical results, from a clinical perspective, among 4 leading technologies currently used in clinical reference laboratories for the analysis of LDL subfractions: gradient gel electrophoresis (GGE), ultracentrifugation-vertical auto profile (VAP), nuclear magnetic resonance (NMR), and tube gel electrophoresis (TGE).
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