Open AccessDetermination of Clopidogrel Resistance by Whole Blood Platelet Aggregometry and Inhibitors of the P2Y12 Receptor
Author(s) -
Boris Ivandic,
Philipp Schlick,
Peter Staritz,
Kerstin Kurz,
Hugo A. Katus,
Evangelos Giannitsis
Publication year - 2006
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.059535
Subject(s) - p2y12 , clopidogrel , platelet , whole blood , platelet aggregation , pharmacology , receptor , medicine , chemistry , aspirin
Inhibition of platelet aggregation by clopidogrel may be insufficient in up to 30% of users. These nonresponders carry an increased risk of cardiovascular events. We reported here a simple assay to study clopidogrel responsiveness.
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