Microfluidic Techniques for Single-Cell Protein Expression Analysis | Zendy

Ethan R Fitzpatrick | Zendy; Sterling E. McBride | Zendy; Jonathan Yavelow | Zendy; Saltanat Najmi | Zendy; P. J. Zanzucchi | Zendy; Robert Wieder | Zendy

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Microfluidic Techniques for Single-Cell Protein Expression Analysis

Author(s) -

Ethan R Fitzpatrick,

Sterling E. McBride,

Jonathan Yavelow,

Saltanat Najmi,

P. J. Zanzucchi,

Robert Wieder

Publication year - 2006

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2005.059014

Subject(s) - microfluidics , protein expression , computational biology , single cell analysis , cell , microbiology and biotechnology , expression (computer science) , chemistry , biology , computer science , nanotechnology , biochemistry , materials science , gene , programming language

The analysis of single cells obtained from needle aspirates of tumors is constrained by the need for processing. To this end, we investigated two microfluidic approaches to measure the expression of surface proteins in single cancer cells or in small populations (<50 cells).

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