Western Blotting of Total Lysate of Helicobacter pylori in Cases of Atrophic Body Gastritis
Author(s) -
Roberta Mini,
Bruno Annibale,
Edith Lahner,
Giulia Bernardini,
Natale Figura,
Annalisa Santucci
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.054627
Subject(s) - atrophic gastritis , helicobacter pylori , gastritis , intestinal metaplasia , serology , gastroenterology , medicine , dysplasia , chronic gastritis , blot , pathology , immunology , biology , antibody , biochemistry , gene
Atrophic body gastritis is considered the first important step in the histogenesis of gastric carcinoma, a multistep process starting from chronic gastritis and progressing through chronic atrophic gastritis, intestinal metaplasia, and dysplasia. Helicobacter pylori is involved in the induction of atrophic body gastritis, but documentation of H. pylori infection is difficult because of the progressive disappearance of the bacterium. Our study aimed to detect past H. pylori infection in patients with atrophic body gastritis.
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