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N-Terminal Pro-B-Type Natriuretic Peptide after High-Dose Chemotherapy: A Marker Predictive of Cardiac Dysfunction?
Author(s) -
Maria Teresa Sandri,
Michela Salvatici,
Daniela Cardinale,
Laura Zorzino,
Rita Passerini,
Paola Lentati,
María Isabel León,
Maurizio Civelli,
Giovanni Martinelli,
Carlo M. Cipolla
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2005.050153
Subject(s) - medicine , natriuretic peptide , isovolumetric contraction , ejection fraction , heart failure , cardiology , chemotherapy , diastole , predictive marker , endocrinology , blood pressure , cancer
Chronic cardiac dysfunction may develop after administration of aggressive chemotherapy, sometimes leading to development of congestive heart failure (CHF). Recently, N-terminal pro-B-type natriuretic peptide (NT-proBNP) was implicated as a marker of CHF. In this study we evaluated the predictive role of NT-proBNP in patients treated with high-dose chemotherapy (HDC).

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