Six Novel Mutations in the Proopiomelanocortin and Melanocortin Receptor 4 Genes in Severely Obese Adults Living in Southern Italy | Zendy

Pasqualina Buono | Zendy; Fabrizio Pasanisi | Zendy; Carmela Nardelli | Zendy; Luigi Ieno | Zendy; Silvana Capone | Zendy; Rosario Liguori | Zendy; Carmine Finelli | Zendy; Giovannangelo Oriani | Zendy; Franco Contaldo | Zendy; Lucia Sacchetti | Zendy

Open Access

Six Novel Mutations in the Proopiomelanocortin and Melanocortin Receptor 4 Genes in Severely Obese Adults Living in Southern Italy

Author(s) -

Pasqualina Buono,

Fabrizio Pasanisi,

Carmela Nardelli,

Luigi Ieno,

Silvana Capone,

Rosario Liguori,

Carmine Finelli,

Giovannangelo Oriani,

Franco Contaldo,

Lucia Sacchetti

Publication year - 2005

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2005.047886

Subject(s) - proopiomelanocortin , melanocortin 4 receptor , medicine , endocrinology , biology , obesity , leptin , body mass index , exon , genetics , melanocortin , gene , hormone

The genetic characterization of obese individuals could clarify the molecular mechanisms underlying body weight regulation and lead to targeted therapy. Here we report variants of the proopiomelanocortin (POMC) and melanocortin receptor 4 (MC4R) genes detected in severely obese adults living in southern Italy.

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