Open AccessMonitoring of Clopidogrel Action: Comparison of Methods
Author(s) -
Jörg Geiger,
Lino L. Teichmann,
Ralf Großmann,
Barsom Aktas,
Udo Steigerwald,
Ulrich Walter,
Reinhard Schinzel
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.047050
Subject(s) - clopidogrel , platelet , p2y12 , medicine , pharmacology , flow cytometry , aspirin , immunology
Clopidogrel is a potent drug for prevention of adverse effects during and after coronary intervention. Increasing experience indicates that a significant proportion of patients do not respond adequately to clopidogrel. Because failure of antiplatelet therapy can have severe consequences, there is need for a reliable assay to quantify the effectiveness of clopidogrel treatment.
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