Technology for Automated, Rapid, and Quantitative PCR or Reverse Transcription-PCR Clinical Testing | Zendy

Siva Raja | Zendy; Jesus Ching | Zendy; Liqiang Xi | Zendy; Steven J. Hughes | Zendy; Ronald Chang | Zendy; Wendy Wong | Zendy; William McMillan | Zendy; William E. Gooding | Zendy; Kenneth S. McCarty | Zendy; Melissa L. Chestney | Zendy; James D. Luketich | Zendy; Tony E. Godfrey | Zendy

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Technology for Automated, Rapid, and Quantitative PCR or Reverse Transcription-PCR Clinical Testing

Author(s) -

Siva Raja,

Jesus Ching,

Liqiang Xi,

Steven J. Hughes,

Ronald Chang,

Wendy Wong,

William McMillan,

William E. Gooding,

Kenneth S. McCarty,

Melissa L. Chestney,

James D. Luketich,

Tony E. Godfrey

Publication year - 2005

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.046474

Subject(s) - genexpert mtb/rif , rna , reverse transcription polymerase chain reaction , lung cancer , rna extraction , medicine , biology , microbiology and biotechnology , pathology , gene , tuberculosis , gene expression , sputum , biochemistry

PCR-based assays can improve clinical care, but they remain technically demanding and labor-intensive. We describe a new instrument, the GeneXpert, that performs automated nucleic acid isolation, reverse transcription, and fluorescence-based quantitative PCR in approximately 35 min.

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