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Multimarker Quantitative Real-Time PCR Detection of Circulating Melanoma Cells in Peripheral Blood: Relation to Disease Stage in Melanoma Patients
Author(s) -
Kazuo Koyanagi,
Christine Kuo,
Taku Nakagawa,
Takuji Mori,
Hideaki Ueno,
Arnulfo R Lorico,
Hong Wang,
E J Hseuh,
Steven O’Day,
Dave S.�B. Hoon
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.045096
Subject(s) - melanoma , medicine , circulating tumor cell , metastasis , cancer , stage (stratigraphy) , peripheral blood , cell , cancer research , oncology , immunology , biology , paleontology , genetics
Detection of melanoma cells in circulation may be important in assessing tumor progression. The objective of this study was to develop a specific, reliable multimarker quantitative real-time reverse transcription-PCR (qRT) assay for detecting melanoma cells in patients' blood.

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