Development of a PCR-Based Assay for Detection, Quantification, and Genotyping of Human Adenoviruses | Zendy

Barbara Chmielewicz | Zendy; Andreas Nitsche | Zendy; Brunhilde Schweiger | Zendy; Heinz Ellerbrok | Zendy

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Development of a PCR-Based Assay for Detection, Quantification, and Genotyping of Human Adenoviruses

Author(s) -

Barbara Chmielewicz,

Andreas Nitsche,

Brunhilde Schweiger,

Heinz Ellerbrok

Publication year - 2005

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.045088

Subject(s) - genotyping , biology , polymerase chain reaction , melting curve analysis , virology , serotype , real time polymerase chain reaction , microbiology and biotechnology , nested polymerase chain reaction , concordance , genotype , gene , genetics

Adenoviruses (AdVs) can cause serious disease in immunosuppressed patients, particularly those undergoing allogeneic stem cell transplantation. A method for virus quantification in clinical specimens is essential for monitoring patient adenoviral loads and evaluating new therapeutic approaches.

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