Open AccessD-Dimer Concentrations in Normal Pregnancy: New Diagnostic Thresholds Are Needed
Author(s) -
Jeffrey A. Kline,
Ginger W Williams,
Jackeline HernandezNino
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.044883
Subject(s) - d dimer , medicine , pregnancy , fibrinogen , preeclampsia , dimer , cutoff , obstetrics , chemistry , genetics , physics , organic chemistry , quantum mechanics , biology
Pregnancy is known to increase the D-dimer concentration above the conventional normal threshold of 0.50 mg/L, leading to an increased false-positive D-dimer test when venous thromboembolism (VTE) is clinically suspected in a pregnant patient. Our aim was to determine the effect of normal pregnancy on the D-dimer concentration.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom