Open AccessThe Uncoupling Protein 2 Ala55Val Polymorphism Is Associated with Diabetes Mellitus: The CARDIA Study
Author(s) -
Xinhua Yu,
David R. Jacobs,
Pamela J. Schreiner,
Myron D. Gross,
Michael W. Steffes,
Myriam Fornage
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.044859
Subject(s) - medicine , diabetes mellitus , insulin resistance , impaired fasting glucose , obesity , endocrinology , abdominal obesity , genotype , incidence (geometry) , glucose homeostasis , impaired glucose tolerance , metabolic syndrome , biology , gene , genetics , physics , optics
Uncoupling proteins (UCPs) reduce ATP generation with concomitant increased release of heat. The activities of UCPs have been related to obesity and energy metabolism.
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