Thyroglobulin Antibodies in Serum of Patients with Differentiated Thyroid Cancer: Relationship between Epitope Specificities and Thyroglobulin Recovery | Zendy

Onyebuchi Okosieme | Zendy; Carol Evans | Zendy; Laura Moss | Zendy; Arthur B. Parkes | Zendy; Lakdasa Premawardhana | Zendy; John H. Lazarus | Zendy

Open Access

Thyroglobulin Antibodies in Serum of Patients with Differentiated Thyroid Cancer: Relationship between Epitope Specificities and Thyroglobulin Recovery

Author(s) -

Onyebuchi Okosieme,

Carol Evans,

Laura Moss,

Arthur B. Parkes,

Lakdasa Premawardhana,

John H. Lazarus

Publication year - 2005

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.044511

Subject(s) - epitope , thyroglobulin , monoclonal antibody , antibody , antigen , medicine , thyroid , thyroid cancer , microbiology and biotechnology , immunology , biology

Serum antibodies against thyroglobulin (TgAbs) are common in patients with differentiated thyroid cancer (DTC) and can interfere in thyroglobulin (Tg) assays. We identified the epitopes on Tg recognized by TgAb-positive sera from patients with DTC and examined the association between epitope specificity patterns and Tg recovery.

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