Open AccessQuantification of Carbamylated LDL in Human Sera by a New Sandwich ELISA
Author(s) -
Eugene O. Apostolov,
Sudhir V. Shah,
Ercan Ok,
Alexei G. Basnakian
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.044032
Subject(s) - chemistry , polyclonal antibodies , chromatography , antibody , reproducibility , high performance liquid chromatography , immunoassay , medicine , immunology
We previously suggested that increased carbamylated LDL (cLDL), a product of nonenzymatic modification of LDL in human serum by urea-derived cyanate, may cause cardiovascular complications in patients with chronic renal insufficiency. An assay for precise measurement of cLDL in serum was not previously available.
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