Open AccessUrinary Osteocalcin as a Marker of Bone Metabolism
Author(s) -
Kaisa K. Ivaska,
Sanna-Maria Käkönen,
Paul Gerdhem,
Karl J. Obrant,
Kim Pettersson,
H. Kalervo Väänänen
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.043901
Subject(s) - bone remodeling , osteocalcin , endocrinology , urine , medicine , metabolism , circadian rhythm , morning , chemistry , alkaline phosphatase , biochemistry , enzyme
Osteocalcin (OC) is produced by osteoblasts during bone formation, and circulating OC has been used in clinical investigations as a marker of bone metabolism. OC is excreted into urine by glomerular filtration and can be found in urine as midmolecule fragments.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom