Poor Agreement among Prothrombin Time International Normalized Ratio Methods: Comparison of Seven Commercial Reagents | Zendy

Juha Horsti | Zendy; Helena Uppa | Zendy; Juhani Vilpo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Poor Agreement among Prothrombin Time International Normalized Ratio Methods: Comparison of Seven Commercial Reagents

Author(s) -

Juha Horsti,

Helena Uppa,

Juhani Vilpo

Publication year - 2005

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.043836

Subject(s) - prothrombin time , medicine , mean difference , clinical practice , significant difference , limits of agreement , clinical trial , confidence interval , nuclear medicine , physical therapy

Prothrombin time (PT) has long been the most popular test for monitoring oral anticoagulation therapy. The International Normalized Ratio (INR) was introduced to overcome the problem of marked variation in PT results among laboratories and the various recommendations for patient care. According to this principle, all reagents should be calibrated to give identical results and the same patient care globally. This is necessary for monitoring of single patients and for application of the results of anticoagulation trials and guidelines to clinical practice.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research