Increased Oxidative DNA Damage, as Assessed by Urinary 8-Hydroxy-2′-Deoxyguanosine Concentrations, and Serum Redox Status in Persons Exposed to Mercury
Author(s) -
Chunying Chen,
Liya Qu,
Yuanyuan Li,
Xing Li,
Guang Jia,
Tiancheng Wang,
Yuxi Gao,
Peiqun Zhang,
Mei Li,
Wei Chen,
Zhifang Chai
Publication year - 2005
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.042093
Subject(s) - 8 hydroxy 2' deoxyguanosine , deoxyguanosine , mercury (programming language) , chemistry , urinary system , urine , redox , dna , oxidative phosphorylation , oxidative damage , dna oxidation , dna damage , oxidative stress , biochemistry , environmental chemistry , medicine , inorganic chemistry , computer science , programming language
Mercury is a ubiquitous and highly toxic environmental pollutant. In this study, we evaluated the relationship between mercury exposure and oxidative stress, serum and urinary mercury concentrations, oxidative DNA damage, and serum redox status in chronically mercury-exposed persons compared with healthy controls.
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