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Biomarker Responses during and after Treatment with Nesiritide Infusion in Patients with Decompensated Chronic Heart Failure
Author(s) -
Wayne L. Miller,
Karen Hartman,
Mary F. Burritt,
Daniel D. Borgeson,
John C. Burnett,
Allan S. Jaffe
Publication year - 2004
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2004.041582
Subject(s) - nesiritide , heart failure , medicine , cardiology , biomarker , acute decompensated heart failure , intensive care medicine , natriuretic peptide , chemistry , biochemistry
Objective methods to assess the adequacy of medication therapy for patients with advanced heart failure are lacking. Serial measurements of biomarkers might be beneficial. Therapy guided by N-terminal pro-B-type natriuretic peptide (NT-proBNP) might be helpful because NT-proBNP should be lowered by therapies that decrease endogenous BNP secretion.

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