Apolipoprotein C-III, n-3 Polyunsaturated Fatty Acids, and “Insulin-Resistant” T−455C APOC3 Gene Polymorphism in Heart Disease Patients: Example of Gene-Diet Interaction | Zendy

Oliviero Olivieri | Zendy; Nicola Martinelli | Zendy; Marco Sandri | Zendy; Antonella Bassi | Zendy; Patrizia Guarini | Zendy; Elisabetta Trabetti | Zendy; Francesca Pizzolo | Zendy; Domenico Girelli | Zendy; Simonetta Friso | Zendy; Pier Franco Pignatti | Zendy; Roberto Corrocher | Zendy

Open Access

Apolipoprotein C-III, n-3 Polyunsaturated Fatty Acids, and “Insulin-Resistant” T−455C APOC3 Gene Polymorphism in Heart Disease Patients: Example of Gene-Diet Interaction

Author(s) -

Oliviero Olivieri,

Nicola Martinelli,

Marco Sandri,

Antonella Bassi,

Patrizia Guarini,

Elisabetta Trabetti,

Francesca Pizzolo,

Domenico Girelli,

Simonetta Friso,

Pier Franco Pignatti,

Roberto Corrocher

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.040477

Subject(s) - docosahexaenoic acid , polyunsaturated fatty acid , medicine , endocrinology , population , apolipoprotein b , genotype , triglyceride , biology , fatty acid , cholesterol , biochemistry , gene , environmental health

Apolipoprotein C-III (apo C-III) is a marker of cardiovascular disease risk associated with triglyceride (TG)-rich lipoproteins. The T-455C polymorphism in the insulin-responsive element of the APOC3 gene influences TG and apo C-III concentrations. Long-chain n-3 polyunsaturated fatty acids (PUFAs) contained in fish have well-known apo C-III-lowering properties.

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