Analysis of Subforms of Free Prostate-Specific Antigen in Serum by Two-Dimensional Gel Electrophoresis: Potential to Improve Diagnosis of Prostate Cancer | Zendy

Klaus Jung | Zendy; Janett Reiche | Zendy; Axel Boehme | Zendy; Carsten Stephan | Zendy; Stephan A. Loening | Zendy; Dietmar Schnorr | Zendy; Wolfgang Hoesel | Zendy; Pranav Sinha | Zendy

Open Access

Analysis of Subforms of Free Prostate-Specific Antigen in Serum by Two-Dimensional Gel Electrophoresis: Potential to Improve Diagnosis of Prostate Cancer

Author(s) -

Klaus Jung,

Janett Reiche,

Axel Boehme,

Carsten Stephan,

Stephan A. Loening,

Dietmar Schnorr,

Wolfgang Hoesel,

Pranav Sinha

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.040469

Subject(s) - prostate cancer , prostate specific antigen , prostate , medicine , prostatic disease , chemistry , urology , chromatography , cancer

The aim of this study was to develop a method to separate and quantify subforms of free prostate-specific antigen (fPSA) in serum by two-dimensional electrophoresis and to assess the diagnostic accuracy of these subforms for prostate cancer (PCa) diagnosis in comparison with total PSA (tPSA) and the ratio of fPSA to tPSA (%fPSA).

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