Comparison of Cardiac Troponin I Immunoassays Variably Affected by Circulating Autoantibodies | Zendy

Susann Eriksson | Zendy; Tuomo Ilva | Zendy; Charlotte Becker | Zendy; Juha Lund | Zendy; Pekka Porela | Zendy; Kari Pulkki | Zendy; LiisaMaria VoipioPulkki | Zendy; Kim Pettersson | Zendy

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Comparison of Cardiac Troponin I Immunoassays Variably Affected by Circulating Autoantibodies

Author(s) -

Susann Eriksson,

Tuomo Ilva,

Charlotte Becker,

Juha Lund,

Pekka Porela,

Kari Pulkki,

LiisaMaria VoipioPulkki,

Kim Pettersson

Publication year - 2005

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.040089

Subject(s) - troponin i , immunoassay , medicine , autoantibody , detection limit , troponin , antibody , chemistry , chromatography , immunology , myocardial infarction

We recently provided evidence that circulating autoantibodies against cardiac troponin I (cTnI) or the troponin complex cause negative interference in cTnI immunoassays. By comparing three cTnI immunoassays, we further explored the phenomenon of circulating autoantibodies and their consequences in patient samples.

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