Diagnostic Probes for Bacillus anthracis Spores Selected from a Landscape Phage Library | Zendy

Jennifer R. Brigati | Zendy; David D. Williams | Zendy; Iryna Sorokulova | Zendy; Viswaprakash Nanduri | Zendy; IHsuan Chen | Zendy; Charles L. Turnbough | Zendy; Valery A. Petrenko | Zendy

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Diagnostic Probes for Bacillus anthracis Spores Selected from a Landscape Phage Library

Author(s) -

Jennifer R. Brigati,

David D. Williams,

Iryna Sorokulova,

Viswaprakash Nanduri,

IHsuan Chen,

Charles L. Turnbough,

Valery A. Petrenko

Publication year - 2004

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2004.038018

Subject(s) - bacillus anthracis , spore , phage display , microbiology and biotechnology , bacillus (shape) , biology , phagemid , bacteriophage , antibody , bacteria , gene , biochemistry , genetics , escherichia coli

Recent use of Bacillus anthracis spores as a bioweapon has highlighted the need for a continuous monitoring system. Current monitoring systems rely on antibody-derived probes, which are not hardy enough to withstand long-term use under extreme conditions. We describe new, phage-derived probes that can be used as robust substitutes for antibodies.

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